Scientific Publications

Michelle Lynn Gill, Ph.D.

Biophysicist and Data Scientist


Publications

Gill, M.L., Sun, S., Byrd, R.A., “Highly quantitative reconstruction of sparsely sampled, low dimensionality NMR spectra”, in preparation.

Gill, M.L., Byrd, R.A., Palmer, A.G. “Detection of chemical exchange in methyl groups of macromolecules”, in preparation.

2017 Tong, M., Pelton, J., Gill, M.L., Zhang, W., Picart, F., Seeliger, M., “Survey of solution dynamics in Src kinase reveals cross talk between the ligand binding and regulatory sites“, Nat. Chem. Biol., submitted.

2016 Gill, M.L., Byrd, R.A., Palmer, A.G. “Dynamics of GCN4 facilitate DNA interaction: a model-free analysis of an intrinsically disordered region“, Phys. Chem. Chem. Phys. 2016, 18, 5839–5849. [pdf]

2015 *Sun, S., *Gill, M.L., Li, Y., Huang, M., Byrd, R.A. “Efficient and generalized processing of multidimensional NUS NMR Data: the NESTA algorithm and comparison of regularization terms”, J. Biomol. NMR 2015, 62, 105–117. [pdf]
* Authors contributed equally

2014 Gill, M.L., Palmer, A.G. “Local isotropic diffusion approximation for coupled internal and overall molecular motions in NMR spin relaxation”, J. Phys. Chem. B 2014, 118, 11120–11128. [pdf]

2014 Gill, M.L., Byrd, R.A. “Dynamic activation of apoptosis: conformational ensembles of cIAP1 are linked to a spring-loaded mechanism”, Nat. Struct. Mol. Biol 2014, 21, 1022–1023. [pdf]

2014 Ergel, B., Gill, M.L., Brown, L., Yu, B., Palmer, A.G., Hunt, J.F. “Protein dynamics control the progression and efficiency of the catalytic reaction cycle of AlkB”, J. Biol. Chem. 2014, 289, 29584–29601. [pdf]

2011 Gill, M.L. and Palmer, A.G. “Multiplet-filtered and gradient-selected zero-quantum TROSY experiments for 13C1H3 methyl groups in proteins”, J. Biomol. NMR, 2011, 51, 245–251. [pdf]

2009 Ramsey, J.D., Gill, M.L., Kamerzell, T.J., Price, E.S., Joshi, S.B., Bishop, S.M., Oliver, C.N., Middaugh, C.R. “Using empirical phase diagrams to understand the role of intramolecular dynamics in immunoglobulin G stability”, J. Pharm. Sci. 2009, 98, 2432–2447. [pdf]

2006 Gill, M.L., Strobel, S.A., and Loria, J.P. “Crystallization and characterization of the thallium form of the Oxytricha nova G-quadruplex”, Nucleic Acids Res. 2006, 34, 4506–4514. [pdf]

2005 Gill, M.L., Strobel, S.A., and Loria, J.P. “205Tl NMR methods for the study of monovalent metal binding sites in nucleic acids”, J. Am. Chem. Soc. 2005, 127, 16723–16732. [pdf]

2005 Beach, H., Cole, R., Gill, M.L., and Loria, J.P. “Conservation of µs-ms enzyme motions in the apo- and substrate-mimicked state”, J. Am. Chem. Soc. 2005, 127, 9167–9176. [pdf]

2004 Adams, P.L., Stahley, M.R., Gill, M.L., Kosek, A.B., Wang, J., and Strobel, S.A. “Crystal structure of a group I intron splicing intermediate”, RNA 2004, 12, 1867–1887. [pdf]

2003 Wiethoff, C.M., Gill, M.L., Koe, G.S., Koe, J.G., and Middaugh, C.R. “A fluorescence study of the structure and accessibility of plasmid DNA condensed with cationic gene delivery vehicles”, J. Pharm. Sci. 2003, 92, 1272–1285. [pdf]

2002 Wiethoff, C.M., Gill, M.L., Koe, G.S., Koe, J.G., and Middaugh, C.R. “The structural organization of cationic lipid-DNA complexes”, J. Biol. Chem. 2002, 277, 44980–44987. [pdf]

2000 Silchenko, S., *Sippel, M.L., Kuchment, O., Benson, D.R., Mauk, A.G., Altuve, A., and Rivera, M. “Hemin is kinetically trapped in cytochrome b5 from rat outer mitochondrial membrane”, Biochem. Biophys. Res. Commun. 2000, 273, 467–472. [pdf]
* M.L. Gill is formerly M.L. Sippel

Selected Research Presentations

2015 Gill, M.L., Sun, S., Li, Y., Huang, M., Byrd, R.A. “NESTA-NMR: efficient and generalized processing of multidimensional NUS NMR data”, Poster, 56th Experimental Nuclear Magnetic Resonance Conference, 2015, Monterrey, CA.

2014 Gill, M.L., Byrd, R.A., Palmer, A.G. “The role of GCN4 conformational dynamics in DNA binding and recognition”, Poster, International Conference of Magnetic Resonance in Biological Sciences, 2014, Dallas, TX.

2012 Gill, M.L., Ergel, B., Brown, L., Yu, B., Palmer, A.G., Hunt, J.F., “Protein dynamics control the progression and efficiency of the catalytic reaction cycle of AlkB”, Poster, International Conference of Magnetic Resonance in Biological Sciences, 2012, Lyon, France.

2011 Gill, M.L., and Palmer, A.G., “Gradient-selected zero-quantum experiments for the study of 1H—13C correlations in protonated methyl groups”, Poster, 52nd Experimental Nuclear Magnetic Resonance Conference, 2011, Monterrey, CA.

2005 Gill, M.L., Strobel, S.A., and Loria, J.P., “Direct study of 205Tl binding to a G-quadruplex by detection of 1H–205Tl scalar couplings”, Selected Oral Presentation, 46th Experimental Nuclear Magnetic Resonance Conference, 2005, Providence, RI.