Michelle Lynn Gill, Ph.D.
Biophysicist and Data Scientist
Gill, M.L., Sun, S., Byrd, R.A., “Highly quantitative reconstruction of sparsely sampled, low dimensionality NMR spectra”, in preparation.
Gill, M.L., Byrd, R.A., Palmer, A.G. “Detection of chemical exchange in methyl groups of macromolecules”, in preparation.
Tong, M., Pelton, J., Gill, M.L., Zhang, W., Picart, F., Seeliger, M., “Survey of solution dynamics in Src kinase reveals cross talk between the ligand binding and regulatory sites“, Nat. Chem. Biol., submitted.
Gill, M.L., Byrd, R.A., Palmer, A.G. “Dynamics of GCN4 facilitate DNA interaction: a model-free analysis of an intrinsically disordered region“, Phys. Chem. Chem. Phys. 2016, 18, 5839–5849. [pdf]
*Sun, S., *Gill, M.L., Li, Y., Huang, M., Byrd, R.A. “Efficient and generalized processing of multidimensional NUS NMR Data: the NESTA algorithm and comparison of regularization terms”, J. Biomol. NMR 2015, 62, 105–117. [pdf]
* Authors contributed equally
Gill, M.L., Palmer, A.G. “Local isotropic diffusion approximation for coupled internal and overall molecular motions in NMR spin relaxation”, J. Phys. Chem. B 2014, 118, 11120–11128. [pdf]
Gill, M.L., Byrd, R.A. “Dynamic activation of apoptosis: conformational ensembles of cIAP1 are linked to a spring-loaded mechanism”, Nat. Struct. Mol. Biol 2014, 21, 1022–1023. [pdf]
Ergel, B., Gill, M.L., Brown, L., Yu, B., Palmer, A.G., Hunt, J.F. “Protein dynamics control the progression and efficiency of the catalytic reaction cycle of AlkB”, J. Biol. Chem. 2014, 289, 29584–29601. [pdf]
Gill, M.L. and Palmer, A.G. “Multiplet-filtered and gradient-selected zero-quantum TROSY experiments for 13C1H3 methyl groups in proteins”, J. Biomol. NMR, 2011, 51, 245–251. [pdf]
Ramsey, J.D., Gill, M.L., Kamerzell, T.J., Price, E.S., Joshi, S.B., Bishop, S.M., Oliver, C.N., Middaugh, C.R. “Using empirical phase diagrams to understand the role of intramolecular dynamics in immunoglobulin G stability”, J. Pharm. Sci. 2009, 98, 2432–2447. [pdf]
Gill, M.L., Strobel, S.A., and Loria, J.P. “Crystallization and characterization of the thallium form of the Oxytricha nova G-quadruplex”, Nucleic Acids Res. 2006, 34, 4506–4514. [pdf]
Gill, M.L., Strobel, S.A., and Loria, J.P. “205Tl NMR methods for the study of monovalent metal binding sites in nucleic acids”, J. Am. Chem. Soc. 2005, 127, 16723–16732. [pdf]
Beach, H., Cole, R., Gill, M.L., and Loria, J.P. “Conservation of µs-ms enzyme motions in the apo- and substrate-mimicked state”, J. Am. Chem. Soc. 2005, 127, 9167–9176. [pdf]
Adams, P.L., Stahley, M.R., Gill, M.L., Kosek, A.B., Wang, J., and Strobel, S.A. “Crystal structure of a group I intron splicing intermediate”, RNA 2004, 12, 1867–1887. [pdf]
Wiethoff, C.M., Gill, M.L., Koe, G.S., Koe, J.G., and Middaugh, C.R. “A fluorescence study of the structure and accessibility of plasmid DNA condensed with cationic gene delivery vehicles”, J. Pharm. Sci. 2003, 92, 1272–1285. [pdf]
Wiethoff, C.M., Gill, M.L., Koe, G.S., Koe, J.G., and Middaugh, C.R. “The structural organization of cationic lipid-DNA complexes”, J. Biol. Chem. 2002, 277, 44980–44987. [pdf]
Silchenko, S., *Sippel, M.L., Kuchment, O., Benson, D.R., Mauk, A.G., Altuve, A., and Rivera, M. “Hemin is kinetically trapped in cytochrome b5 from rat outer mitochondrial membrane”, Biochem. Biophys. Res. Commun. 2000, 273, 467–472. [pdf]
* M.L. Gill is formerly M.L. Sippel
Selected Research Presentations
Gill, M.L., Sun, S., Li, Y., Huang, M., Byrd, R.A. “NESTA-NMR: efficient and generalized processing of multidimensional NUS NMR data”, Poster, 56th Experimental Nuclear Magnetic Resonance Conference, 2015, Monterrey, CA.
Gill, M.L., Byrd, R.A., Palmer, A.G. “The role of GCN4 conformational dynamics in DNA binding and recognition”, Poster, International Conference of Magnetic Resonance in Biological Sciences, 2014, Dallas, TX.
Gill, M.L., Ergel, B., Brown, L., Yu, B., Palmer, A.G., Hunt, J.F., “Protein dynamics control the progression and efficiency of the catalytic reaction cycle of AlkB”, Poster, International Conference of Magnetic Resonance in Biological Sciences, 2012, Lyon, France.
Gill, M.L., and Palmer, A.G., “Gradient-selected zero-quantum experiments for the study of 1H—13C correlations in protonated methyl groups”, Poster, 52nd Experimental Nuclear Magnetic Resonance Conference, 2011, Monterrey, CA.
Gill, M.L., Strobel, S.A., and Loria, J.P., “Direct study of 205Tl binding to a G-quadruplex by detection of 1H–205Tl scalar couplings”, Selected Oral Presentation, 46th Experimental Nuclear Magnetic Resonance Conference, 2005, Providence, RI.